Murdoch struggles to work with the new coroner and clashes openly when a cement block found near the water contains the remains of not one but three men.

Members of a squad of Canadian soldiers who were recently deployed to South Africa are stricken with a mysterious illness and others are being murdered.

Ignoring a puzzling break-in at Station 4, Murdoch travels to Buffalo to help Dr. Ogden solve the suspicious death of a young cancer patient at a children's hospital.

Dark secrets surface at the Jenkins household when Murdoch questions the family and servants of murdered patriarch Percival Jenkins.

A flamboyant Parisian detective arrives in Toronto and insinuates himself into the disappearance of a French woman visiting her married sister.

Murdock comes across a made-to-scale diorama of a cul-de-sac Toronto street replete with miniature residents and discovers evidence that at murder took place there.

Det. Murdoch and Const. Crabtree investigate when a body is uncovered by workmen. The remains are quite old and date from perhaps the mid-1860s. Dr. Ogden's review of the remains indicate that he might have been murdered. Among the remains is a gin flask with a note secreted in a false bottom. The note is signed by none other than the man who would later become Canada's first Prime Minister, Sir John A. MacDonald. The dead man is soon identified and Murdoch's old nemesis from Ottawa, spook Terence Meyers, is on the scene as well. A surprise visitor to the station gives them vital information about the theft of $1 million in gold and a connection to the U.S. Civil War.

A telephone operator with ambitions to be a detective believes she's heard a woman strangled on an open line but Brackenreid is reluctant to believe her.

While investigating a lethal gunshot on a trolley that no one seems to have heard, Murdoch finds that a disappearance may be linked to his old girlfriend, Anna Fulford.

When a convent tries to bury one of its most venerated members in the churchyard, they find another body in the plot and Murdoch is reunited with his sister.

The murder of a young student in an exclusive girls' school leads Murdoch to conclude that someone posing as a vampire is preying on several of the young girls.

A Robin Hood-like bank robber with a flair for style kisses pretty female bank employees before donating the money to a local orphanage.

A man is found murdered at a Lewis Carroll costume party. All clues point to the guest dressed as the Mad Hatter.