Renowned archeologist and expert in the occult, Dr. Indiana Jones, is hired by the U.S. Government to find the Ark of the Covenant, which is believed to still hold the ten commandments. Unfortunately, agents of Hitler are also after the Ark. Indy, and his ex-flame Marion, escape from various close scrapes in a quest that takes them from Nepal to Cairo.

After being driven away from Honduras, as well as offending the King of Madagascar, Adventurer-Archaeologist Indiana Jones, in the company of Wilhelmina Scott and Short Round, barely manage to escape from Chinese gangsters on a plane. Unfortunately, its engines fail, the trio bail out and land in a Gujarati-speaking village of Pankot in British India. Once there they find out that the region is poverty-stricken, all children are untraceable due to missing stones that were once blessed by Bhagwan Shri Shankar. A trip to the local Maharaja's palace does not reveal the whereabouts of the children, but Indiana locates a hidden underground passage. The passage leads to the human sacrificial venue of Devi Maa Kali by a local thuggee priest, Mola Ram. They locate 2 of the 3 missing precious stones, Indiana keeps one, and must be on the run from Mola - who is determined to catch and kill them at any and all cost.

Indiana Jones, famed adventurer and archaeologist acquires a diary that holds clues and a map with no names to find the mysterious Holy Grail- which was sent from his father, Dr. Henry Jones, in Italy. Upon hearing from a private collector, Walter Donavan, that the mission for the Holy Grail went astray with the disappearance of his father, Indiana Jones and museum curator Marcus Brody venture to Italy in search of Indy's father. However, upon retrieving Dr. Henry Jones in Nazi territory, the rescue mission turns into a race to find the Holy Grail before the Nazis do- who plan to use it for complete world domination for their super-race. With the diary as a vital key and the map with no names as a guide, Indiana Jones once again finds himself in another death defying adventure of pure excitement.

During the Cold War, Soviet agents watch Professor Henry Jones when a young man brings him a coded message from an aged, demented colleague, Henry Oxley. Led by the brilliant Irina Spalko, the Soviets tail Jones and the young man, Mutt, to Peru. With Oxley's code, they find a legendary skull made of a single piece of quartz. If Jones can deliver the skull to its rightful place, all may be well; but if Irina takes it to its origin, she'll gain powers that could endanger the West. Aging professor and young buck join forces with a woman from Jones's past to face the dangers of the jungle, Russia, and the supernatural.